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科研招聘| 英国牛津大学博后位置 Dunn School of Pathology

LABXPRO 2020-04-03 14:20:15

Postdoctoral Research Associates at Dunn School of Pathology, University of Oxford


Applications are invited for two Postdoctoral Research Associates to join Dr Dragana Ahel’s group at the Dunn School of Pathology. The main research area of Dragana Ahel’s laboratory is studying cellular pathways that maintain genome stability and play roles in human disease. The laboratory uses a multidisciplinary approach to study relevant protein factors at a biochemical, cellular, and physiological level. 

     
DR. DRAGANA AHEL

Mechanisms of genome stability




More information about the Ahel laboratory is available on the group’s website http://ahel-d.path.ox.ac.uk/.


The posts will be held at the Dunn School of Pathology, a world-class biomedical research Department at the University of Oxford. The Dunn School is based on the vibrant South Parks Road Science Campus in the heart of Oxford. Its research benefits from exceptionally strong scientific community and outstanding facilities.

Two positions are currently available: one suitable for candidates with the background in cell biology and genetics, and another for candidates with expertise in biochemistry and structural biology. Applicants should have a PhD in cell biology, biochemistry, or a related field, and a track record of publishing at an internationally-competitive level. Required skills include high level of competence in general molecular biology techniques, cell biology, protein biochemistry, genetics or protein crystallography. Experience in DNA repair, DNA replication, and broader area of genome stability would be an advantage, but is not necessary.

If you have an excellent background in biomedical sciences and a strong publication record, we want to hear from you!

For further details please visit: https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_details_form.jobspec?p_id=133038 https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_details_form.jobspec?p_id=133039

The closing date for applications is Friday 16 February 2018. Interviews will be held as soon as possible thereafter. For informal enquires please contact Dragana Ahel via email dragana.ahel@path.ox.ac.uk.

Relevant Publications

Sebesta M, Cooper CDO, Ariza A, Carnie CJ, Ahel D.

2017

Structural insights into the function of ZRANB3 in replication stress response.

Nat. Commun. 8:15847.

Sharifi,R, Morra,R, Denise Appel,C, Tallis,M, Chioza,B, Jankevicius,G, Simpson,M.A, Matic,I, Ozkan,E, Golia,B, Schellenberg,M.J, Weston,R, Williams,J.G, Rossi,M.N, Galehdari,H, Krahn,J, Wan,A, Trembath,R.C, Crosby,A.H, Ahel,D, Hay,R, Ladurner,A.G

2013

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.

EMBO J. 32: 1225-37

Weston, R., Peteers, H., and Ahel, D.

2012

ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response.

Genes Dev 26: 1558-72.

Mehrotra, P.V., Ahel, D., Ryan, D.P., Weston, R., Wiechens, N., Kraehenbuehl, R., Owen-Hughes, T., and Ahel, I.

2011

DNA repair factor APLF is a histone chaperone.

Mol Cell 41: 46-55.